Receptor Activator of Nuclear Factor-kappa B

A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

Also Known As:

TRANCE-R; CD265 Antigen; NF-KappaB Receptor Activator; RANK Protein; Receptor Activator of NF-kappa B; Receptor Activator of NF-kappaB; Receptor Activator of Nuclear Factor-kappaB; TNFRSF11A Protein; TRANCE Receptor; Activator, NF-KappaB Receptor; Antigen, CD265; NF Kappa B Receptor Activator; NF KappaB Receptor Activator; Receptor Activator of NF kappa B; Receptor Activator of NF kappaB; Receptor Activator of Nuclear Factor kappa B; Receptor Activator of Nuclear Factor kappaB; Receptor Activator, NF-KappaB; TRANCE R; NF-Kappa B Receptor Activator; Receptors, Tumor Necrosis Factor, Member 11a; Tumor Necrosis Factor Receptor Superfamily, Member 11a

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Cytokine Receptors: 1620
        Tumor Necrosis Factor Receptors: 3685
        Receptor Activator of Nuclear Factor-kappa B: 379

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Disease

Drug/Important Bio-Agent (IBA)